RDP2: recombination detection and analysis from sequence alignments
Top Cited Papers
Open Access
- 17 September 2004
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 21 (2) , 260-262
- https://doi.org/10.1093/bioinformatics/bth490
Abstract
Summary: RDP2 is a Windows 95/XP program that examines nucleotide sequence alignments and attempts to identify recombinant sequences and recombination breakpoints using 10 published recombination detection methods, including GENECONV, BOOTSCAN, MAXIMUM χ2, CHIMAERA and SISTER SCANNING. The program enables fast automated analysis of large alignments (up to 300 sequences containing 13 000 sites), and interactive exploration, management and verification of results with different recombination detection and tree drawing methods. Availability: RDP2 is available free from the RDP2 website (http://darwin.uvigo.es/rdp/rdp.html) Contact:darren@science.uct.ac.za Supplementary information: Detailed descriptions of RDP2 and the methods it implements are included in the program manual, which can be downloaded from the RDP2 website.Keywords
This publication has 15 references indexed in Scilit:
- Evaluation of Methods for Detecting Recombination from DNA Sequences: Empirical DataMolecular Biology and Evolution, 2002
- The Effect of Recombination on the Accuracy of Phylogeny EstimationJournal of Molecular Evolution, 2002
- Evaluation of methods for detecting recombination from DNA sequences: Computer simulationsProceedings of the National Academy of Sciences, 2001
- Recombination and the Molecular ClockMolecular Biology and Evolution, 2000
- Sister-Scanning: a Monte Carlo procedure for assessing signals in recombinant sequencesBioinformatics, 2000
- Possible Emergence of New Geminiviruses by Frequent RecombinationVirology, 1999
- A program for calculating and displaying compatibility matrices as an aid in determining reticulate evolution in molecular sequencesBioinformatics, 1996
- Identification of Breakpoints in Intergenotypic Recombinants of HIV Type 1 by BootscanningAIDS Research and Human Retroviruses, 1995
- fastDNAml: a tool for construction of phylogenetic trees of DNA sequences using maximum likelihoodBioinformatics, 1994
- Analyzing the mosaic structure of genesJournal of Molecular Evolution, 1992