Clinical experience with a hypotonic oral rehydration solution in acute diarrhoea
- 21 January 1993
- journal article
- clinical trial
- Published by Wiley in Acta Paediatrica
- Vol. 82 (1) , 52-54
- https://doi.org/10.1111/j.1651-2227.1993.tb12516.x
Abstract
A hypotonic oral rehydration salts (ORS) solution with total osmolality of 224 mosmol/l was compared in an open clinical trial with an isotonic (osmolality 304 mosmol/l) ORS solution for the treatment of dehydration due to acute diarrhoea. Both ORS solutions had the same electrolyte composition with a Na+ concentration of 60 mmol/l. Children given the hypotonic ORS solution (n = 103) passed significantly fewer diarrhoeal stools, and their diarrhoea and hospital stay were shorter than those of children given the isotonic ORS solution (n = 135). We conclude that hypotonic ORS ("light" ORS) has clinical advantages over the standard ORS currently used in Finland.Keywords
This publication has 7 references indexed in Scilit:
- The Role of Human Perfusion Techniques in the Assessment of Oral Rehydration SolutionsActa Paediatrica, 1989
- Disease‐related Animal Models for Optimising Oral Rehydration Solution CompositionActa Paediatrica, 1989
- Optimising Oral Rehydration Solution Composition in Model Systems: Studies in Normal Mammalian Small IntestineActa Paediatrica, 1989
- Overview of Childhood Acute Diarrhoea in Europe: Implications for Oral Rehydration TherapyActa Paediatrica, 1989
- Optimising Oral Rehydration Solution Composition for the Children of Europe: Clinical TrialsActa Paediatrica, 1989
- Evaluation of an Oral Rehydration Solution with Na+ 60 mmol/l in Infants Hospitalized for Acute Diarrhoea or Treated as OutpatientsActa Paediatrica, 1985
- Oral Rehydration, Rapid Feeding, and Cholestyramine for Treatment of Acute DiarrheaJournal of Pediatric Gastroenterology and Nutrition, 1985