An inverse relation between mitochondrial hexokinase content and phosphoglucomutase activity of rat tissues
- 1 November 1977
- journal article
- conference paper
- Published by Springer Nature in Molecular and Cellular Biochemistry
- Vol. 18 (1) , 39-47
- https://doi.org/10.1007/bf00215278
Abstract
The hexokinase: fumarase ratios of mitochondria isolated from ten tissues of the rat were determined, and compared with the tissue content of phosphoglucomutase and phosphorylase, taken as representatives of enzymes concerned with glycogen metabolism. A generally inverse relationship was found between the mitochondrial hexokinase: fumarase ratio and phosphoglucomutase levels. The cytochrome: fumarase ratios were relatively invariant in these same mitochondria. The results are interpreted as indicating a specialization of mitochondria, with increased amounts of hexokinase being associated with the mitochondria in tissues exhibiting less dependence on glycogen metabolism, as judged from phosphoglucomutase levels.This publication has 45 references indexed in Scilit:
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