P53 null mice: damaging the hypothesis?
- 18 September 2000
- journal article
- review article
- Published by Elsevier in Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
- Vol. 452 (2) , 149-162
- https://doi.org/10.1016/s0027-5107(00)00089-0
Abstract
No abstract availableKeywords
This publication has 68 references indexed in Scilit:
- The p53 pathwayThe Journal of Pathology, 1999
- The dual role model for p53 in maintaining genomic integrityCellular and Molecular Life Sciences, 1999
- Mdm2 promotes the rapid degradation of p53Nature, 1997
- Structure and Function of the p53 Tumor Suppressor Gene: Clues for Rational Cancer Therapeutic StrategiesJNCI Journal of the National Cancer Institute, 1996
- p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.Proceedings of the National Academy of Sciences, 1995
- p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatchesCell, 1995
- Tumor spectrum analysis in p53-mutant miceCurrent Biology, 1994
- Apoptosis in Carcinogenesis: The Role of p53Cold Spring Harbor Symposia on Quantitative Biology, 1994
- Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumoursNature, 1992
- Commitment to senescence: A model for the finite and infinite growth of diploid and transformed human fibroblasts in cultureJournal of Theoretical Biology, 1975