Monoclonal Antibodies Specific for Sendai Virus I. Production and Characterization of Monoclonal Antibodies
- 1 September 1986
- journal article
- research article
- Published by Wiley in Scandinavian Journal of Immunology
- Vol. 24 (3) , 335-340
- https://doi.org/10.1111/j.1365-3083.1986.tb02102.x
Abstract
Twelve monoclonal antibodies specific for Sendai virus were prepared by fusing immune LOU rat spleen cells with Y3 or FO myeloma cells. Six antibodies bound the viral glycoprotein HN, and six the viral protein F. Among the six HN-specific monoclonal antibodies, five reacted with the very same epitope and inhibited viral haemagglutination. Two antibodies against the F protein recognized the same epitope, but all the others reacted with different epitopes. All monoclonals were characterized with regard to specificity, biological function, epitope recognition, isotypes, and pI.Keywords
This publication has 46 references indexed in Scilit:
- Studies of Monoclonal Antibodies Specific for Major Histocompatibility Complex Products of the RatScandinavian Journal of Immunology, 1985
- Studies of Monoclonal Antibodies Specific for Major Histocompatibility Complex Products of the RatScandinavian Journal of Immunology, 1985
- Studies of Monoclonal Antibodies Specific for Major Histocompatibility Complex Products of the RatScandinavian Journal of Immunology, 1985
- Immune Response to Hepatitis B Surface Antigen: Enhancement by Prior Injection of Antibodies to the IdiotypeScience, 1983
- Immunization of mice against African trypanosomiasis using anti-idiotypic antibodies.The Journal of Experimental Medicine, 1982
- The strain A anti‐p‐azophenylarsonate major crossreactive idiotypic family includes members with no reactivity toward p‐azophenylarsonateEuropean Journal of Immunology, 1981
- Genetic control of the immune response to staphylococcal nuclease XI. Effects of in vivo administration of anti‐idiotypic antibodiesEuropean Journal of Immunology, 1981
- Antigen- and receptor-driven regulatory mechanisms. III. Induction of delayed type hypersensitivity to azobenzenearsonate with anti-cross-reactive idiotypic antibodies.The Journal of Experimental Medicine, 1980
- Subclass restriction of murine antibodies. II. The IgG plaque-forming cell response to thymus-independent type 1 and type 2 antigens in normal mice and mice expressing an X-linked immunodeficiency.The Journal of Experimental Medicine, 1980
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970