Decomposition of Iodine-Labelled Antipyrine

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Abstract
The radiochemical stability of 4-iodoantipyrine-123 and 4-iodo-antipyrine-123I was examined under different circumstances by paper chromatography. The essential conclusions were (1) Use preferably the 123I-labelled compound. (2) Dilute the compound with water and not with saline. (3) Analyse each batch for radiochemical purity. (4) Although temperature is not a major factor in the decomposition of 4-iodoantipyrine storage at the lowest convenient temperature is advisable. (5) Purify the 131I-labelled compound before use.