microRNA Functions
Top Cited Papers
- 1 November 2007
- journal article
- review article
- Published by Annual Reviews in Annual Review of Cell and Developmental Biology
- Vol. 23 (1) , 175-205
- https://doi.org/10.1146/annurev.cellbio.23.090506.123406
Abstract
MicroRNAs (miRNAs) are small noncoding RNAs that play important roles in posttranscriptional gene regulation. In animal cells, miRNAs regulate their targets by translational inhibition and mRNA destabilization. Here, we review recent work in animal models that provide insight into the diverse roles of miRNAs in vivo.Keywords
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