The Biosynthesis of p-Aminobenzoic Acid by Symbiosis Experiments.

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Abstract
Although Streptococcus faecalis R and Lactobacillus arabinosus 17-5 grow together, but not alone, in a medium lacking folic acid and phenylalanine, they do not grow if p-aminobenzoic acid is lacking. L. arabinosus thus cannot synthesize p-aminobenzoic and folic acids in the absence of phenylalanine. The latter may replace p-aminobenzoic acid but is competitively inhibited by sulfanilamide. A mechanism for the conversion of phenylalanine into p-aminobenzoic acid is proposed.