Rapid Determination of Proteins in Serum and Cerebrospinal Fluid by Laser-Nephelometry
- 1 January 1978
- journal article
- research article
- Published by Walter de Gruyter GmbH in cclm
- Vol. 16 (11) , 631-635
- https://doi.org/10.1515/cclm.1978.16.11.631
Abstract
The laser-nephelometric technique is characterized by its easy handling, accuracy, good reproducibility and especially by the short time in which reliable results are available. A very good correlation was found between the results obtained by electroimmunoassay and those obtained by laser-nephelometry. In both techniques .alpha.2-macroglobulin is the largest serum protein that can be determined in normal unconcentrated [human] CSF. This is of diagnostic significance, since the serum/CSF ratios of both albumin and .alpha.2-macroglobulin are used as a parameter for the blood-CSF barrier condition.This publication has 15 references indexed in Scilit:
- Serum-CSF protein gradients, the blood-CSF barrier and the local immune responseZeitschrift für Neurologie, 1978
- Protein profile of cerebrospinal fluid in multiple sclerosis with special reference to the function of the blood brain barrierZeitschrift für Neurologie, 1977
- A turbidimetric immuno assay (TIA) with automated individual blank compensationClinica Chimica Acta; International Journal of Clinical Chemistry, 1977
- Some Problems in the Correction for Intrinsic Light-Scattering of Samples in Specific Protein Analysis by Automated ImmunoprecipitationAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1977
- Hydrodynamic Radii versus Molecular Weights in Clearance Studies of Urine and Cerebrospinal FluidAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1977
- Evaluation of the blood-CSF barrier by protein gradients and the humoral immune response within the central nervous systemJournal of the Neurological Sciences, 1976
- Estimation of the stokes radii of serum proteins for a study of protein movement from blood to amniotic fluidBiochimica et Biophysica Acta (BBA) - Protein Structure, 1976
- Étude quantitative des immunoglobulines G et de l'albumine du liquide cephalo rachidienClinica Chimica Acta; International Journal of Clinical Chemistry, 1972
- Quantitative Estimation of Human Immunoglobulins Following Carbamylation by Electrophoresis in Antibody-containing AgaroseScandinavian Journal of Clinical and Laboratory Investigation, 1968
- Immunochemical quantitation of antigens by single radial immunodiffusionImmunochemistry, 1965