Three Unexpected Products of Peroxidase Reaction; Brain Site of Lesion, Beriberi Poison and New Disease
- 1 January 1964
- journal article
- research article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 83 (2) , 103-113
- https://doi.org/10.1620/tjem.83.103
Abstract
In 1922 I published with Sekiya a new peroxidase reaction (often quoted in the literature as Sato and Sekiya''s peroxidase stain or as Sato''s peroxidase reaction). As my proper object of research was infantile nutrition, I made light of our own peroxidase reaction[long dash]which was then used only for the differentiation of myeloic and lymphatic leucocytes in leukemic cases (then very rare). But in course of time it gave me a hint to finding 1) the localisation of a brain lesion, 2) the poison of infantile beriberi (methyl glyoxal 1934; strictly chemical indentification 1950) and 3) a new disease (Chediak-Higashi''s Disease).Keywords
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