Dual Infection of Dogs with Distemper Virus and Virus of Infectious Canine Hepatitis.
- 1 November 1952
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 81 (2) , 461-463
- https://doi.org/10.3181/00379727-81-19911
Abstract
Both distemper and infectious hepatitis virus have a high incidence rate and following a report of inclusion bodies of both viruses in the same dog, studies were undertaken to determine whether the 2 could infect dogs simultaneously, whether there would be discernible interference and what the effects might be of such a concurrent infection. Following injn. of distemper virus and infectious canine hepatitis virus singly and mixed, it was found that the mixture of viruses produced a more severe type of illness in dogs than either virus alone. In the same dog both viruses were present in the blood during the acute phase of illness, inclusion bodies of both viruses were found and immunity against both viruses developed. Dogs recovered from distemper and then given infective blood containing infectious hepatitis virus showed an illness which resembled that of dual infection.Keywords
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