Effect of Cholic and Hyodeoxycholic Acids on Metabolism of Exogenous Cholesterol in Mice.
- 1 February 1960
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 103 (2) , 385-387
- https://doi.org/10.3181/00379727-103-25529
Abstract
Observations were made on the effects of cholic and hyodeoxycholic acids on the metabolism of cholesterol of exogenous origin in mice. Mice were fed diets supplemented with these bile acids, with cholesterol or with a combination of bile acids and cholesterol. Cholic acid caused the accumulation of large amounts of liver and carcass cholesterol. On the other hand hyodeoxycholic acid prevented liver and carcass cholesterol accumulation, and reversed the effects of cholic acid.Keywords
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