STUDIES OF THE THYROID APPARATUS. L

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Abstract
Distortion of differential development follows both thyroid and parathyroid removal. With the exception of the hypophysis, the submaxillaries, and possibly the spleen, this is not due to any specific relation of glandular functions to organ growth, but to the general metabolic disturbance induced by the deficiencies. The growth of some organs is more resistant and that of others more sensitive than that of the body as a whole. The basis of this differential reaction lies in the relation of the metabolic processes of the organs in question to the bodily economy as a whole. The distortion is consistent in direction and produces a distinctly modified type of structural organization. The broader aspects of this finding are referred to in their relation to evolutionary development.