Total Synthesis of (−)-Okilactomycin
- 13 November 2007
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 129 (48) , 14872-14874
- https://doi.org/10.1021/ja077569l
Abstract
A highly convergent synthesis of (−)-okilactomycin is described. Key reactions of this synthesis include a strategy-level diastereoselective oxy-Cope rearrangement/oxidation sequence, a Petasis−Ferrier union/rearrangement tactic, and an efficient RCM reaction to construct the 13-membered macrocyclic ring.Keywords
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