FLUORESCEIN AND INDOCYANINE GREEN FLUORESCENCE ANGIOGRAPHY IN STUDY OF AFFECTED MALES AND IN FEMALE CARRIERS WITH CHOROIDERMIA

Publisher Website
Google Scholar
Abstract
Male (26) and female (13) carriers of different ages with choroideremia of varying severity were investigated using sodium fluorescein (FAG) and/or indocyanine green (ICG) fluorescence angiography. Females with minor changes present in pigment epithelium may stay unchanged throughout life or gradually develop into a more advanced stage resembling the fundus picture of severely affected males. In moderately affected females there was a patchy degeneration of pigment epithelium in the macula. Peripapillary degeneration was also seen in indocyanine green fluorescence angiograms. In males, atrophic areas and the remaining choriocapillaris were clearly demonstrated in FAG and were less well visible in ICG angiograms. ICG angiograms showed choroidal vessels more clearly in cases where the pigment epithelium and the choriocapillaris were still present. In advanced cases in males and females, the choroidal blood circulation was slow.

This publication has 4 references indexed in Scilit: