Oxytetracycline biosynthesis: mode of incorporation of [1-13C]- and [1,2-13C2]-acetate
- 1 January 1983
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 3,p. 128-130
- https://doi.org/10.1039/c39830000128
Abstract
Determination of the mode of incorporation of [1-13C]- and [1,2-13C2]-acetate into oxytetracycline by Streptomyces rimosus, has established the exclusive polyketide origin of the tetracyclic nucleus and the direction of folding of a hypothetical linear intermediate.Keywords
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