Methotrexate resistance and gene amplification. Mechanisms and implications
- 15 May 1986
- Vol. 57 (10) , 1912-1917
- https://doi.org/10.1002/1097-0142(19860515)57:10<1912::aid-cncr2820571004>3.0.co;2-o
Abstract
No abstract availableThis publication has 46 references indexed in Scilit:
- Ultrastructural features of minute chromosomes in a methotrexate-resistant mouse 3T3 cell lineProceedings of the National Academy of Sciences, 1985
- Gene amplification in cultured animal cellsCell, 1984
- Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea.Molecular and Cellular Biology, 1983
- Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines.Molecular and Cellular Biology, 1981
- Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line.Molecular and Cellular Biology, 1981
- Unstable amplification of an altered dihydrofolate reductase gene associated with double-minute chromosomesPublished by Elsevier ,1981
- Chromosomal and Extrachromosomal Localization of Amplified Dihydrofolate Reductase Genes in Cultured Mammalian CellsPublished by Cold Spring Harbor Laboratory ,1981
- Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes.Proceedings of the National Academy of Sciences, 1979
- Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.Proceedings of the National Academy of Sciences, 1978
- Metaphase Chromosome Anomaly: Association with Drug Resistance and Cell-Specific ProductsScience, 1976