Hemocompatibility of Hydrogel with Polyethyleneoxide Chains
- 1 April 1987
- journal article
- research article
- Published by SAGE Publications in Journal of Biomaterials Applications
- Vol. 2 (2) , 219-234
- https://doi.org/10.1177/088532828700200203
Abstract
We have synthesized a hydrogel with long polyethyleneoxide (PEO) chains and evaluated its hemocompatibility. The hydrogel significantly suppressed the adsorption of plasma proteins and adhesion of platelets. In addition, the marked retardation of thrombus formation on its surface was recognized. These findings seems to be caused by the volume restriction effects derived from the highly flexible and hydrophilic PEO chains.Keywords
This publication has 8 references indexed in Scilit:
- Application of an Antithrombogenic Anthron® Bypass Tube to Experimental Orthotopic Liver TransplantationAnnual Northeast Bioengineering Conference, 1986
- Interaction Between Blood Components and Hydrogels With Poly(Oxyethylene) ChainsPublished by Springer Nature ,1984
- Cross-linking of alpha 2-plasmin inhibitor to fibrin by fibrin-stabilizing factor.Journal of Clinical Investigation, 1980
- Blood‐compatibility‐water‐content relationships for radiation‐grafted hydrogelsJournal of Polymer Science: Polymer Symposia, 1979
- HYDROPHOBIC POLYMER SURFACES AND THEIR INTERACTIONS WITH BLOOD*Annals of the New York Academy of Sciences, 1977
- COAGULATION FACTORS AND THE ROLE OF SURFACE IN THEIR ACTIVATIONAnnals of the New York Academy of Sciences, 1977
- Platelet adhesion and contact activation time tests on HEMA coated cellulose acetate membranesJournal of Biomedical Materials Research, 1975
- WATER AS A BIOMATERIALAsaio Journal, 1973