Sequence features responsible for intron retention in human
Open Access
- 1 January 2007
- journal article
- Published by Springer Nature in BMC Genomics
- Vol. 8 (1) , 59
- https://doi.org/10.1186/1471-2164-8-59
Abstract
One of the least common types of alternative splicing is the complete retention of an intron in a mature transcript. Intron retention (IR) is believed to be the result of intron, rather than exon, definition associated with failure of the recognition of weak splice sites flanking short introns. Although studies on individual retained introns have been published, few systematic surveys of large amounts of data have been conducted on the mechanisms that lead to IR.Keywords
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