An audit of immunisation status of sickle cell patients in Coventry, UK
- 22 December 2008
- journal article
- research article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 62 (1) , 42-45
- https://doi.org/10.1136/jcp.2008.058982
Abstract
Protection against infection is a key aim of any care programme for patients with sickle cell disorders, and is one of the stated objectives of the UK national neonatal screening programme. An audit of the immunisation status of the 58 sickle cell patients living in Coventry was carried out against UK national guidance (2006). Among 25 children (aged ⩽16 years), 14 (56%) had complete immunisation against pneumococcus,Haemophilus influenzaetype b (Hib) and meningococcus group C (MenC), with eight (32%) having some coverage, and three (12%) having none at all. Among 33 adults, only four patients (12%) had complete coverage, with up-to-date coverage against pneumococcus 21%, Hib 18% and MenC 15%. Current (ie, within the last year) immunisation against viral influenza was found in only 12% of adults and 8% of children. These rates are similar to those found in other UK studies. If the potential benefits of neonatal screening are to be realised, an effective immunisation programme is essential. There are key roles for haemoglobinopathy nurse specialists, and the proposed national haemoglobinopathy database, in improving the rates of immunisation coverage.Keywords
This publication has 18 references indexed in Scilit:
- Incidence of Invasive Pneumococcal Disease among Individuals with Sickle Cell Disease before and after the Introduction of the Pneumococcal Conjugate VaccineClinical Infectious Diseases, 2007
- Uptake of pneumococcal polysaccharide vaccine in at-risk populations in England and Wales 1999–2005Epidemiology and Infection, 2007
- Pneumococcal vaccines for sickle cell diseaseCochrane Database of Systematic Reviews, 2004
- Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysaccharide vaccinationThe Journal of Pediatrics, 2003
- Combined schedule of 7-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal vaccine in children and young adults with sickle cell diseaseThe Journal of Pediatrics, 1998
- Bacteremia in sickle hemoglobinopathiesThe Journal of Pediatrics, 1986
- Prophylaxis with Oral Penicillin in Children with Sickle Cell AnemiaNew England Journal of Medicine, 1986
- Infections in children with sickle cell anemiaJournal of Pediatric Hematology/Oncology, 1982
- Sickle Cell Anemia and Severe Infections Due to Encapsulated BacteriaThe Journal of Infectious Diseases, 1977
- BACTERIAL INFECTION AND SICKLE CELL ANEMIAMedicine, 1971