Studies on the Course of Recurrent Endogenous Affective Disorders

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Abstract
Comparison of rates of relapse before lithium administration and after double-blind and open discontinuation has shown (a) that the course of severe endogenous affective disorders is not easily influenced by the attitude of the doctor or the patient, and (b) that there is a high risk of further relapses in a group of patients who have had 2 or more episodes within a period of 2 years.

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