Stability of Vancomycin and Aminoglycoside Antibiotics in Peritoneal Dialysis Concentrate
- 1 January 1981
- journal article
- research article
- Published by S. Karger AG in Nephron
- Vol. 28 (5) , 241-243
- https://doi.org/10.1159/000182208
Abstract
The stability in peritoneal dialysis concentrate of vancomycin and five aminoglycoside antibiotics was measured over 24 h. Vancomycin, gentamicin, siscmicin, and netilmicin are sufficiently stable that these drugs can be added to the dialysis concentrate when peritoneal administration of the antibiotic is indicated in patients undergoing chronic peritoneal dialysis. Tobramycin is the most labile of the aminoglycoside antibiotics; if administered intraperitoneally in dialysis concentrate, it must be used promptly after reconstitution.Keywords
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