DEGENERATIVE JOINT DISEASE OF THE HIP

Publisher Website
Google Scholar
Abstract
Degenerative joint disease is a manifestation of aging, the result of the wear and tear of living on articular structures. Pathologically, there is a change in the articular cartilage leading to fibrillation of the cartilage followed by eburnation of bone and overproduction of bone exostoses. When the damaged joint is in an abnormal position, acute symptoms may result from acute or sustained trauma following normal structural stress and strain, and during the acute phase an inflammation of the synovia is usually seen. In all instances, there is a certain element of overproduction of connective tissue manifested by granulation tissue in the form of pannus. Since we have felt that hyperadrenalism induced by corticotropin (ACTH) or cortisone may interfere with inflammatory reactions in the connective tissue and delay the turnover of granulations,1 it was decided to evaluate the effect of cortisone on degenerative joint disease. Many forms of this disease