Adverse reactions to tiaprofenic acid mimicking interstitial cystitis

Publisher Website
Google Scholar
Abstract
Case 1 - A 66 year old woman had been prescribed tiaprofenic acid 300 mg twice a day for three years before referral. Other medication included bendro-fluazide 2.5 mg once a day, clonidine hydrochloride 50 μg twice a day, and Codydramol (dihydrocodeine and paracetamol) as needed. She developed frequency and haematuria. Urine culture showed sterile pyuria, cystoscopy a small inflamed bladder, and biopsy interstitial cystitis. She was admitted for ileal conduit formation, but first it was decided to withdraw tiaprofenic acid. Within five months her only symptom was nocturia.