Efficient synthesis of new 5-substituted uracil nucleosides useful for linker arm incorporation
- 1 January 1994
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 17,p. 1997-1998
- https://doi.org/10.1039/c39940001997
Abstract
5-Substituted uracil nucleosides useful for the attachment of linker arms to nucleic acids are prepared from arabinoaminooxazoline and dimethyl α-bromomethylfumarate in a short reaction sequence without using any protecting groups, and incorporated into oligodeoxyribonucleotides.Keywords
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