COMBINATION CHEMOTHERAPY OF METASTATIC THYROID-CANCER - PHASE-II STUDY

  • 1 January 1983
    • journal article
    • research article
    • Vol. 6  (5) , 579-581
Abstract
Eleven patients with metastatic thyroid cancer received combination chemotherapy with doxorubicin, bleomycin, vincristine and melphalan. Six of 11 patients responded, 2 with a minor response, 3 with a partial response and 1 with a complete response. Most responses were brief (2-3 mo.), but the patient with a complete response is alive and free of disease at 60+ mo. Toxicity was moderate and predominantly hematologic. Thyroid carcinoma is a moderately sensitive neoplasm with occasional prolonged responses to chemotherapy.