THE INFLUENCE OF POTASSIUM ION UPON GLUCOSE UPTAKE AND GLYCOGEN SYNTHESIS IN THE ISOLATED RAT DIAPHRAGM

Publisher Website
Google Scholar
Abstract
The amounts of glucose taken from a medium, and the amounts of glycogen synthesized, by rat hemidiaphragms were studied under various conditions. High concentrations of potassium ion inhibited the glucose uptake and there was also a reduced net glycogen synthesis. Glycogen breakdown was probably not increased by high potassium ion concentration. The effect of potassium was most marked when conditions were such that one would ordinarily expect a considerable glucose uptake or glycogen synthesis. The action of insulin was not peculiarly susceptible to potassium ion inhibition.