Abstract
White rats from a colony inbred for 25 generations under conditions of continuous light exhibited a prompt response to an artificial 16-hr, day. Eight hours of warm and light alternating with 8 hrs. of cold and dark caused the rats to establish activity rhythms with the peaks of activity correlated with the dark and cold periods. Neither time of feeding nor time of solar day influenced the artificial 16-hr. rhythm. The estrous cycle was not significantly affected.

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