THE EFFECT OF CARBOHYDRATE FEEDING ON THE OUTPUT OF URINARY AMINO ACID

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Abstract
In order to obtain further information on the protein sparing mechanism induced by carbohydrates a study was made of the urinary amino acid excretion patterns prevailing after admn. of carbohydrate. The results of these expts. showed that in the infant and the adult the urinary output of total N, amino N, and tryptophane was reduced below normal values in the 3 hr. period following the admn. of single doses of various carbohydrates . The output of the 8 other amino acids measured was not significantly affected so it appears that the sparing action involves tryptophane and components of the undetd. fraction of the urinary amino acids. The observation that the mechanism involves tryptophane which is considered to be neither ketogenic nor glucogenic, lends support to the prevailing view that the phenomenon is not due to a simple transposition of energy either in the form of calories or chemical radicals.

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