A New Method for the Introduction of Trifluoromethyl Groups
- 1 December 1977
- journal article
- research article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 16 (12) , 854-855
- https://doi.org/10.1002/anie.197708541
Abstract
The first general trifluoromethylation of alkanes has now been discovered. The CF3 substituent provides a means of making unstable molecules isolable; in addition, CF3 derivatives often exhibit enhanced pharmacological activity. equation imageKeywords
This publication has 6 references indexed in Scilit:
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- The Chemistry of Sulfur Tetrafluoride. II. The Fluorination of Organic Carbonyl Compounds1Journal of the American Chemical Society, 1960
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