A chemotyping scheme for clinical isolates of Haemophilus influenzae

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Abstract
A total of 464 H. influenzae strains, most of them fresh clinical isolates, were classified by chemotyping, a combination of auxotyping and biotyping. Seven auxotests and 4 other biochemical tests allowed recognition of 56 types. These were to a degree site-specific. H. influenzae of capsular type b proved almost without exception to belong to 1 chemotype and 24 of 33 strains assigned to this chemotype were capsulated. When surgical-ward isolates of H. influenzae were typed, the results suggested that some cross-infection had occurred.