Use of Testosterone Propionate and Estrogenic Substance in Treatment of Essential Hypertension, Angina Pectoris and Peripheral Vascular Disease

Publisher Website
Google Scholar
Abstract
82 patients were treated with androgen estrogenic substance; observations made over a period of 3[image] yrs. Fifty six had essential hypertension; 12 had angina pectoris, and 14 exhibited occlusive peripheral vascular disease. Sex hormones were administered by intra-musc. inj. and during the period of sex hormone therapy all other general and specific therapeutic measures were suspended. Among the group of hypertensive patients the fall in blood pressure was more pronounced and more prolonged than that obtained by other medical measures. On cessation of therapy the blood pressure usually returned to previous levels. The response among patients with angina pectoris was unusually good as manifested by any increase in tolerance to all precipitating factors, decrease in frequency and severity of attacks, and a decrease in the severity of pain if attacks continued. Improvement in patients with peripheral vascular disease was manifested by a decrease or a complete cessation of pain, healing of gangrenous ulcers, return of normal color and temp., and occasionally an improvement in the oscillometric indices. Patients with advanced vascular damage were apparently benefited by such treatment.