Abstract
The theories surrounding the mode of action of antibiotics are explored in the light of varying degrees of growth stimulation obtained under different exptl. conditions. Presence of antibiotics could modify growth by: (1) elimination of known pathogens, (2) elimination of microorganisms that depress growth either by toxin formation or through competition for essential nutrients, (3) modification of bacterial metabolism or production of antibiotic-resistant strains with modified metabolism, or (4) elimination of antibiotic-sensitive organisms, leading to increased growth of other types which could perhaps synthesize essential nutrients or else not compete for essential nutrients.