Organogermanium Compounds. New Simplified Synthesis of Germatranes Substituted with Novel Functional Groups

1 January 1985

journal article
research article
Published by The Japan Institute of Heterocyclic Chemistry in HETEROCYCLES

Vol. 23 (6) , 1493-1496
https://doi.org/10.3987/r-1985-06-1493

Abstract

New general methods for the synthesis of 5-substituted germatranes [showing antitumor activity] (4) were directly developed using the corresponding germyl adducts (2) obtained by germylation of .alpha.,.beta.-unsaturated compounds (1) with trichlorogermane.

Keywords

HETEROCYCLES

This publication has 1 reference indexed in Scilit:

CYTO-TOXIC EFFECTS AND BIOLOGICAL-ACTIVITY OF 2-AZA-8-GERMANSPIRO[4,5]-DECANE-2-PROPANAMINE-8,8-DIETHYL-N,N-DIMETHYLDICHLORIDE (NSC 192965 - SPIROGERMANIUM) INVITRO
1982