THYROID IN B-12 DEFICIENT CHICK EMBRYOS1

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Abstract
AN ENLARGED thyroid gland was observed in B-12 deficient chick embryos during the study of the pathologic changes associated with this deficiency (1, 2). The extreme enlargement of the gland was not apparent when vitamin B-12 was injected either parenterally into the hens maintained on the low B-12 diet or when injected directly into the eggs prior to incubation (1). The pathologic changes in the thyroid of these B-12 deficient embryos are now reported.