Use of Alveolar Macrophages for Cultivation of Canine Distemper Virus.
- 1 November 1967
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 126 (2) , 571-574
- https://doi.org/10.3181/00379727-126-32509
Abstract
Cell cultures prepared from dog lungs without trypsinization contained viable lung macrophages. When such cultures were inoculated with CDV, giant cells were seen 2 to 6 days after inoculation. When virulent CDV was titrated in dog lung macrophages and in dogs, comparable endpoints were obtained. Giant cell formation in lung macrophage cultures, therefore, permitted demonstration and assay of virulent CDV.This publication has 0 references indexed in Scilit: