EVALUATION OF LITHIUM-THERAPY FOR ALCOHOLISM

  • 1 January 1984
    • journal article
    • research article
    • Vol. 45  (12) , 494-499
Abstract
The efficacy of Li therapy for alcoholism was examined in 84 alcoholic volunteers admitted for rehabilitation. Subjects were randomly assigned to a Li or placebo treatment condition for 18 mo. and were reinterviewed monthly to document their compliance, drinking status and mood. Two separate factors contributed to abstinent outcome: therapeutic serum Li levels (.gtoreq. 0.4 meq/l) and medication compliance. Recommendations are proposed for studying compliance effects in future treatment studies.

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