A critique of pancreas transplantation

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Abstract
There are three possible indications for pancreas transplantation** 1. to correct the diabetic state; 2. to cure or ameliorate the complications of diabetes or to delay or diminish their deterioration; 3. to prevent the complications. The diabetes we are considering here is type 1 or insulin‐dependent diabetes, a disorder in which there is more or less complete insulin deficiency. No one has suggested pancreas transplantation for type 2, non‐insulin dependent diabetes. This article questions the rationale of pancreas transplantation. It maintains that the value of the procedure has not been established.