Effect of Cortisone on Healing of Corneal Wounds

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Abstract
Cortisone was administered subconjunctivally to rabbits in a daily dose of 2.5 mg. or 15 mg. This inhibited the formation of the fibrinous coagulum, cellular infiltration, fibroblastic repair and endothelial regeneration during the reparative phase of central perforating corneal wounds. The inhibition was much more marked with the larger dose of cortisone. Epithelial regeneration was affected only by this latter dose.

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