THE EFFECTS OF LISINOPRIL ON RENAL FUNCTION IN PROTEINURIC RENAL TRANSPLANT RECIPIENTS

Publisher Website
Google Scholar
Abstract
Renal transplantation is frequently accompanied by systemic hypertenion. In the present study we evaluated the effect of 2.5 mg lisinopril in 12 hypertensive and proteinuric renal graft recipients with stable graft function over 3 months. Only patients with absence of renal artery stenosis, at least as judged by technetium-scan imaging, were included. Lisinopril was effective in lowering systemic blood pressure. Mean arterial pressure was unchanged despite reduction of concomitant anti-hypertensive medication. Mean serum creatinine was unchanged during the study (1.95±0.8 mg/dl in the pre-treatment period vs. 1.77±0.76 mg/dl in the intervention period, n.s.). Glomerular filtration rate remained stable (62.75±21.96 vs. 60.17±18.27 ml/min/1.73 m2, n.s.) whereas renal plasma flow increased (224.75±91.66 vs. 244.92±94.13 ml/min/1.73m2, P

This publication has 0 references indexed in Scilit: