Diels–Alder reactions involving cis-1,2-isopropylidenedioxycyclohexa-3,5-diene and enzymatic resolution of one of the adducts

Abstract
cis-1,2-Isopropylidenedioxycyclohexa-3,5-diene undergoes Diels–Alder [4 + 2] cycloaddition reactions with a variety of dienophiles including dimethyl acetylenedicarboxylate; the adduct formed with the latter dienophile was hydrolysed stereoselectively by pig liver esterase.

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