Rate of Collagen Formation in Biopsy-Connective Tissue of the Rat

Publisher Website
Google Scholar
Abstract
(1) Collagen was found initially in connective tissue biopsy of male and female rats at 7 days following sponge implantation. (2) Collagen content of connective tissue biopsy increased rapidly in both sexes during the first 14 days of tissue growth. (3) After 21 days of connective tissue development in the female, collagen content remained constant up to 300 days of tissue age while in the male, collagen content continued to increase as the tissue aged. (4) The percentage of total scleroprotein which was solubilized by 0.5 M acetic acid decreased with tissue age and this decrease was greater in the 300-day-old tissue of the male rat than in comparable tissue of the female.