Role of the Rep Helicase Gene in Homologous Recombination in Neisseria gonorrhoeae
Open Access
- 15 April 2005
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 187 (8) , 2903-2907
- https://doi.org/10.1128/jb.187.8.2903-2907.2005
Abstract
In Escherichia coli , the Rep helicase has been implicated in replication fork progression, replication restart, homologous recombination, and DNA repair. We show that a Neisseria gonorrhoeae rep mutant is deficient in the homologous-recombination-mediated processes of DNA transformation and pilus-based colony variation but not in DNA repair.Keywords
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