Lipoprotein(a)
- 1 June 1999
- journal article
- review article
- Published by Wolters Kluwer Health in Current Opinion in Lipidology
- Vol. 10 (3) , 225-236
- https://doi.org/10.1097/00041433-199906000-00005
Abstract
Lipoprotein(a) is an atherogenic, cholesterol ester-rich lipoprotein of unknown physiological function. The unusual species distribution of lipoprotein(a) and the extreme polymorphic nature of its distinguishing apolipoprotein component, apolipoprotein(a), have provided unique challenges for the investigation of its biochemistry, genetics, metabolism and atherogenicity. Some fundamental questions regarding this enigmatic lipoprotein have escaped elucidation, as will be highlighted in this review.Keywords
This publication has 149 references indexed in Scilit:
- The Apolipoprotein(a) Promoter Contains a Retinoid Response ElementBiochemical and Biophysical Research Communications, 1998
- Apolipoprotein(a) Yeast Artificial Chromosome Transgenic RabbitsPublished by Elsevier ,1998
- The Apo(a) Gene is the Major Determinant of Variation in Plasma Lp(a) Levels in African AmericansAmerican Journal of Human Genetics, 1997
- Oxidized lipoprotein (a) induces cell adhesion molecule Mac-1 (CD 11b) and enhances adhesion of the monocytic cell line U937 to cultured endothelial cellsAtherosclerosis, 1996
- Site-specific Mutagenesis Demonstrates That Cysteine 4326 of Apolipoprotein B Is Required for Covalent Linkage with Apolipoprotein(a) in VivoPublished by Elsevier ,1995
- The Recurring Evolution of Lipoprotein(a)Journal of Biological Chemistry, 1995
- Identification of Two Functionally Distinct Lysine-binding Sites in Kringle 37 and in Kringles 32−36 of Human Apolipoprotein(a)Published by Elsevier ,1995
- Tissue distribution of [3H]cholesteryl linoleyl ether-labeled human Lp(a) in different rat organsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1988
- Teaching old dogmas new tricksNature, 1987
- cDNA sequence of human apolipoprotein(a) is homologous to plasminogenNature, 1987