Nucleotide sequence definition of a major human repeated DNA, the Hind III 1.9 kb family
Open Access
- 25 May 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 10 (10) , 3211-3219
- https://doi.org/10.1093/nar/10.10.3211
Abstract
A human Hind III 1.9 kb repeated DNA fragment was isolated and cloned in pBR322. A cloned member that hybridized predominantly to the 1.9 kb Hind III band in a digest of whole human DNA was chosen for sequencing. It is an 1894 bp fragment that shows no significant internal repeats. Few pCG residues are observed in the sequence and there are numerous stop codons. Detailed sequence comparisons confirm this is a novel class of repeats that is not related to previously characterized human satellite DNAs or Alu sequences. At least a portion of the sequence described is conserved in evolution.Keywords
This publication has 15 references indexed in Scilit:
- Structural analysis of interspersed repetitive polymerase III transcription units in human DNA.1981
- Nudeotide sequence of mouse satellite DNANucleic Acids Research, 1981
- DNA Methylation and Gene FunctionScience, 1980
- Sequence definition and organization of a human repeated DNAJournal of Molecular Biology, 1980
- Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes.Proceedings of the National Academy of Sciences, 1980
- Novel classes of mouse repeated DNAsNucleic Acids Research, 1980
- Complex and simple sequences in human repeated DNAsChromosoma, 1978
- Repeating restriction fragments of human DNANucleic Acids Research, 1976
- Improved Estimation of Secondary Structure in Ribonucleic AcidsNature New Biology, 1973
- Properties of a supercoiled deoxyribonucleic acid-protein relaxation complex and strand specificity of the relaxation eventBiochemistry, 1970