The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCFβ-TrCP E3 Ligase
Open Access
- 1 November 2010
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 285 (48) , 37159-37169
- https://doi.org/10.1074/jbc.m110.152942
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCFβ-TRCPGenes & Development, 2010
- Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65Molecular and Cellular Biology, 2006
- TAZ: A β-Catenin-like Molecule that Regulates Mesenchymal Stem Cell DifferentiationCell Cycle, 2005
- The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosisNature Cell Biology, 2005
- A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt–Oram syndromeProceedings of the National Academy of Sciences, 2005
- TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell DifferentiationScience, 2005
- The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAPCell, 2005
- Control of Cell Proliferation and Apoptosis by Mob as Tumor Suppressor, MatsCell, 2005
- IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effectsOncogene, 2000
- Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tauScience, 2000