Biodegradable Polyester, Poly[α-(4-Aminobutyl)-l-Glycolic Acid], as a Non-Toxic Gene Carrier
- 1 January 2000
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 17 (7) , 811-816
- https://doi.org/10.1023/a:1007552007765
Abstract
Purpose.The aim of this study was to develop a non-toxic polymericgene carrier. For this purpose, biodegradable cationic polymer,poly[α-(4-aminobutyl)-l-glycolic acid] (PAGA) was synthesized. PAGA...Keywords
This publication has 21 references indexed in Scilit:
- Pharmacokinetic considerations in somatic gene therapyAdvanced Drug Delivery Reviews, 1998
- Nanoparticle DNA Carrier with Poly(l-lysine) Grafted Polysaccharide Copolymer and Poly(d,l-lactic acid)Bioconjugate Chemistry, 1997
- Structure of DNA-Cationic Liposome Complexes: DNA Intercalation in Multilamellar Membranes in Distinct Interhelical Packing RegimesScience, 1997
- Gene Transfer Mediated by Polyarginine Requires a Formation of Big Carrier-Complex of DNA AggregateBiochemical and Biophysical Research Communications, 1997
- Characterization of Vectors for Gene Therapy Formed by Self-Assembly of DNA with Synthetic Block Co-PolymersHuman Gene Therapy, 1996
- Activation of the Complement System by Synthetic DNA Complexes: A Potential Barrier for Intravenous Gene DeliveryHuman Gene Therapy, 1996
- Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA − Immunodeficient PatientsScience, 1995
- Transfection of Folate-Polylysine DNA Complexes: Evidence for Lysosomal DeliveryBioconjugate Chemistry, 1995
- DNA Complexes with Polycations for the Delivery of Genetic Material into CellsBioconjugate Chemistry, 1995
- Lipophilic polylysines mediate efficient DNA transfection in mammalian cellsBiochimica et Biophysica Acta (BBA) - Biomembranes, 1991