Factor VIII-related activities after 1-deamino-8-D-arginine vasopressin in multicentric reticulohistiocytosis
- 1 January 1984
- journal article
- research article
- Published by Springer Nature in La Ricerca in Clinica e in Laboratorio
- Vol. 14 (1) , 37-39
- https://doi.org/10.1007/bf02905038
Abstract
Summary A woman with multicentric reticulohistiocytosis, having symptoms including bleeding and a borderline level of factor VIII, was given an i.v. infusion of DDAVP as a pharmacological test to evaluate the release of factor VIII-related properties from storage sites. The results show a reduced response to DDAVP in the patient in comparison with a normal control subject. This could be due either to a defect in the release of the factor VIII complex after DDAVP or to a reduced synthesis and/or storage capacity by the storage cells.Keywords
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