Leukocytes from Patients Allergic to Chromium and Nickel Examined by the Sealed Capillary Migration Technique
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 70 (1) , 30-33
- https://doi.org/10.1159/000233269
Abstract
Leukocytes from patients allergic to chromium and nickel were studied by a sealed capillary migration test. The migration indices were determined at 2, 5 and 24 h. The chromium-allergic group could be differentiated from the control group at all investigated times, and especially at 2 and 5 h, by using a potassium dichromate concentration of 1.7 × 10––5M in the capillaries. The migration indices in the nickel-allergic group could not be used for discrimination from the controls. The highest chromate (1.1 × 10––4M) and nickel sulfate (3.8 × 10––4M) concentrations inhibited the migration of leukocytes from both patients and controls, indicating toxic effects.Keywords
This publication has 1 reference indexed in Scilit:
- Leukocyte migration inhibition assay (LIF) in nickel contact dermatitisArchives of Dermatology, 1976