Intraneural Colchicine Inhibition of Adenoviral and Adeno-associated Viral Vector Remote Spinal Cord Gene Delivery
- 1 February 2003
- journal article
- Published by Wolters Kluwer Health in Neurosurgery
- Vol. 52 (2) , 381-387
- https://doi.org/10.1227/01.neu.0000044459.24519.3e
Abstract
OBJECTIVE. The mechanism of remote viral gene delivery to the spinal cord is unknown. The present experiment demonstrates that intraneural injection ofKeywords
This publication has 31 references indexed in Scilit:
- Targeted Retrograde Gene Delivery for Neuronal ProtectionMolecular Therapy, 2002
- Remote Delivery of rAAV‐GFP to the Rat Brainstem Through the Recurrent Laryngeal NerveThe Laryngoscope, 2001
- Streptozotocin-Induced Diabetes Causes Metabolic Changes and Alterations in Neurotrophin Content and Retrograde Transport in the Cervical Vagus NerveExperimental Neurology, 2001
- Sequestration of Adenoviral Vector by Kupffer Cells Leads to a Nonlinear Dose Response of Transduction in LiverMolecular Therapy, 2001
- Gene delivery to in situ veins: Differential effects of adenovirus and adeno-associated viral vectorsJournal of Vascular Surgery, 2000
- Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous systemProceedings of the National Academy of Sciences, 2000
- Neuroprotection of Spinal Motoneurons Following Targeted Transduction with an Adenoviral Vector Carrying the Gene for Glial Cell Line-Derived Neurotrophic FactorExperimental Neurology, 1998
- Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neurone diseasesNeuroReport, 1995
- Stepwise dismantling of adenovirus 2 during entry into cellsCell, 1993
- Integrins αvβ3 and αvβ5 promote adenovirus internalization but not virus attachmentCell, 1993